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Diagnostic tools for poverty-related diseases

Activities: Others

Funds for NGOs 

The purpose of this Call for Proposals is to provide funding to projects focusing on validation of the clinical performance and/or implementation of new or improved diagnostic tools and technologies for detection of any of the PRDs, including as co-infections.

Background: Disease diagnosis in sub-Saharan Africa is highly challenging, as the population is predominantly rural and the health care systems often have limited resources. Early and rapid diagnosis of poverty-related diseases (PRDs)(1) offers the best opportunity for patients to receive timely and appropriate treatment, but adequate diagnostic tools are not readily available because of a lack of drive to develop and deploy them in disease-endemic countries. Therefore, there is a clear need for the development and uptake of rapid, accurate, cost-effective, scalable and field-friendly diagnostic tools.

Scope: The purpose of this Call for Proposals is to provide funding to projects focusing on validation of the clinical performance and/or implementation of new or improved diagnostic tools and technologies for detection of any of the PRDs, including as co-infections. These tools and technologies should improve the performance of diagnosis, prediction, monitoring, intervention or assessment of therapeutic response, with a significant impact on clinical decision and health outcomes. Applications should focus on late stage development (e.g. evaluation and/or demonstration phase trials) or implementation studies in sub-Saharan Africa. Applications should further provide detailed plans for World Health Organisation (WHO) endorsement and/or implementation of the diagnostic tools and technologies upon successful completion of the project. Proposals focused entirely on early-stage, laboratory-based studies using biobanked samples are outside the scope of this call. Priority will be given to point-of-care diagnostics for use in resource-limited settings.

EDCTP considers that proposals of between 36 and 60 months duration would allow this specific challenge to be addressed appropriately. Nonetheless, this does not preclude submission and selection of proposals for activities of a different duration.

Expected impact: Projects funded under this Call for Proposals should lead to improvements in patient care through early detection and treatment of disease and/or enhanced monitoring and tracking of disease progression and therapeutic response. Projects should thus contribute towards the implementation of innovative, rapid and simple diagnostics that can be deployed at low cost in health systems in resource-poor settings.

Eligibility:

Consortia comprising a minimum of three different legal entities are eligible to apply. Two of the legal entities must be established in two different European Participating States(2) of the EDCTP Association and one of the legal entities must be established in a sub-Saharan African country(3). All three legal entities must be independent of each other.

Notes:
1.For this call, poverty-related diseases (PRDs) include HIV/AIDS, malaria, tuberculosis and the following neglected infectious diseases (NIDs): dengue/severe dengue; rabies; human African trypanosomiasis (sleeping sickness); Leishmaniases; cysticercosis/taeniasis; dracunculiasis (guinea-worm disease); echinococcosise; foodborne trematodiases; lymphatic filariasis; onchocerciasis (river blindness); schistosomiasis; soil-transmitted helminthiases; Buruli ulcer; leprosy (Hansen disease); trachoma; yaws; as well as emerging infectious diseases of particular relevance for Africa, such as Ebola.


2.Legal entities in the following European countries: Austria, Denmark, Finland, France, Germany, Ireland, Italy, Luxembourg, the Netherlands, Norway, Portugal, Spain, and the United Kingdom.


3.Legal entities in the following sub-Saharan African countries are eligible to apply:
Angola, Benin, Botswana, Burkina Faso, Burundi, Cameroon, Cape Verde, Central African Republic, Chad, Comoros, Democratic Republic of Congo, Republic of Congo, Djibouti, Equatorial Guinea, Eritrea, Ethiopia, Gabon, The Gambia, Ghana, Guinea, Guinea-Bissau, Ivory Coast, Kenya, Lesotho, Liberia, Madagascar, Malawi, Mali, Mauritania, Mauritius, Mozambique, Namibia, Niger, Nigeria, Rwanda, São Tomé & Príncipe, Senegal, Seychelles, Sierra Leone, Somalia, South Sudan, South Africa, Sudan, Swaziland, Tanzania, Togo, Uganda, Zambia and Zimbabwe.

Stage 2:
Open date:
        30 April 2015
Close date:        7 July 2015
Call Budget:     15M Euros
Funding level: 100% of eligible costs
Expected number of grants:     4-8

Application Process

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